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Tacrolimus nanoparticles based on chitosan combined with nicotinamide: enhancing percutaneous delivery and treatment efficacy for atopic dermatitis and reducing dose

BACKGROUND: Topical application of tacrolimus (FK506) was effective in the treatment of atopic dermatitis (AD); however, adverse effects frequently occurred with the increase of FK506 dose during long–term treatment. OBJECTIVE: The objective of this project was to develop a hybrid skin targeting sys...

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Detalles Bibliográficos
Autores principales:	Yu, Kaiyue, Wang, Yixuan, Wan, Tao, Zhai, Yuanhao, Cao, Sisi, Ruan, Wenyi, Wu, Chuanbin, Xu, Yuehong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743175/ https://www.ncbi.nlm.nih.gov/pubmed/29317821 http://dx.doi.org/10.2147/IJN.S150319

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