Quercetin suppresses DNA double-strand break repair and enhances the radiosensitivity of human ovarian cancer cells via p53-dependent endoplasmic reticulum stress pathway

Quercetin is proven to have anticancer effects for many cancers. However, the role of tumor suppressor p53 on quercetin’s radiosensitization and regulation of endoplasmic reticulum (ER) stress response in this process remains obscure. Here, quercetin exposure resulted in ER stress, prolonged DNA rep...

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Detalles Bibliográficos
Autores principales: Gong, Cheng, Yang, Zongyuan, Zhang, Lingyun, Wang, Yuehua, Gong, Wei, Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743179/
https://www.ncbi.nlm.nih.gov/pubmed/29317830
http://dx.doi.org/10.2147/OTT.S147316

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