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Lipopolysaccharide-induced inflammation in monocytes/macrophages is blocked by liposomal delivery of G(i)-protein inhibitor

BACKGROUND: Lipopolysaccharide (LPS) is widely recognized as a potent activator of monocytes/macrophages, and its effects include an altered production of key mediators, such as inflammatory cytokines and chemokines. The involvement of G(i) protein in mediating LPS effects has been demonstrated in m...

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Detalles Bibliográficos
Autores principales: Tucureanu, Monica Madalina, Rebleanu, Daniela, Constantinescu, Cristina Ana, Deleanu, Mariana, Voicu, Geanina, Butoi, Elena, Calin, Manuela, Manduteanu, Ileana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743190/
https://www.ncbi.nlm.nih.gov/pubmed/29317816
http://dx.doi.org/10.2147/IJN.S150918