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Channel opening and gating mechanism in AMPA-subtype glutamate receptors
AMPA-subtype ionotropic glutamate receptors mediate fast excitatory neurotransmission throughout the central nervous system. Gated by the neurotransmitter glutamate, AMPA receptors are critical for synaptic strength and dysregulation of AMPA receptor-mediated signaling is linked to numerous neurolog...
Autores principales: | Twomey, Edward C., Yelshanskaya, Maria V., Grassucci, Robert A., Frank, Joachim, Sobolevsky, Alexander I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743206/ https://www.ncbi.nlm.nih.gov/pubmed/28737760 http://dx.doi.org/10.1038/nature23479 |
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