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Lineage specification of human dendritic cell is marked by expression of the transcriptionl factor IRF8 in HSCs and MPPs

The origin and specification of human dendritic cells (DCs) have not been investigated at clonal level. Using clonal assays combined with statistical computation to quantify the yield of granulocytes, monocytes, lymphocytes and three subsets of DCs from single human CD34(+) progenitor cells, we show...

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Detalles Bibliográficos
Autores principales:	Lee, Jaeyop, Zhou, Yu Jerry, Ma, Wenji, Zhang, Wanwei, Aljoufi, Arafat, Luh, Thomas, Lucero, Kimberly, Liang, Deguang, Thomsen, Matthew, Bhagat, Govind, Shen, Yufeng, Liu, Kang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743223/ https://www.ncbi.nlm.nih.gov/pubmed/28650480 http://dx.doi.org/10.1038/ni.3789

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