Cargando…

AJAP1 expression modulates glioma cell motility and correlates with tumor growth and survival

Glioblastoma multiforme (GBM) is one of the most common primary malignant brain tumors. Unraveling the molecular and genetic complexity that determines GBM's pronounced migratory property could provide new options for therapeutic targeting that may significantly complement current surgical and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Di, Chunhui, Mladkova, Nikol, Lin, James, Fee, Brian, Rivas, Miriam, Chunsheng, Kang, Bigner, Darell, Adamson, David Cory
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743336/ https://www.ncbi.nlm.nih.gov/pubmed/29115565 http://dx.doi.org/10.3892/ijo.2017.4184

Ejemplares similares

Tumor-associated methylation of the putative tumor suppressor AJAP1 gene and association between decreased AJAP1 expression and shorter survival in patients with glioma
por: Cogdell, David, et al.
Publicado: (2011)

Glioblastoma Multiforme Oncogenomics and Signaling Pathways
por: Kanu, Okezie O., et al.
Publicado: (2009)

Endogenous AJAP1 associates with the cytoskeleton and attenuates angiogenesis in endothelial cells
por: Hötte, Katharina, et al.
Publicado: (2017)

Expression Patterns of Ezrin and AJAP1 and Clinical Significance in Breast Cancer
por: Xu, Cong, et al.
Publicado: (2022)

A novel recombinant immunotoxin-based therapy targeting wild-type and mutant EGFR improves survival in murine models of glioblastoma
por: Chandramohan, Vidyalakshmi, et al.
Publicado: (2013)

Deregulated AJAP1/β-catenin/ZEB1 signaling promotes hepatocellular carcinoma carcinogenesis and metastasis
por: Han, Jihua, et al.
Publicado: (2017)

MiR‐552 promotes the proliferation, migration and EMT of hepatocellular carcinoma cells by inhibiting AJAP1 expression
por: Qu, Weiqing, et al.
Publicado: (2018)

Downregulation of TET1 Promotes Bladder Cancer Cell Proliferation and Invasion by Reducing DNA Hydroxymethylation of AJAP1
por: Yan, Yi-lin, et al.
Publicado: (2020)

SYST-12 D2C7 CAR: A NOVEL CAR T CELL THAT SIMULTANEOUSLY TARGETS WILDTYPE EGFR AND ITS MUTANT ISOFORM EGFRVIII FOR TREATMENT OF GLIOMA AND BRAIN METASTASES
por: Wilkinson, Daniel, et al.
Publicado: (2022)

β-Catenin nuclear localization positively feeds back on EGF/EGFR-attenuated AJAP1 expression in breast cancer
por: Xu, Cong, et al.
Publicado: (2019)

LncRNA FGF14‐AS2 represses growth of prostate carcinoma cells via modulating miR‐96‐5p/AJAP1 axis
por: Li, Rubing, et al.
Publicado: (2021)

Vinculin modulation of paxillin–FAK interactions regulates ERK to control survival and motility
por: Subauste, M. Cecilia, et al.
Publicado: (2004)

2-Hydroxyglutarate Production, but Not Dominant Negative Function, Is Conferred by Glioma-Derived NADP(+)-Dependent Isocitrate Dehydrogenase Mutations
por: Jin, Genglin, et al.
Publicado: (2011)

Modulation of Motility and Proliferation of Glioma Cells by Hepatocyte Growth Factor
por: Yamamoto, Shinji, et al.
Publicado: (1997)

Transvaginal sonographic evaluation at different menstrual cycle phases in diagnosis of uterine lesions
por: Hajishaiha, Masomeh, et al.
Publicado: (2011)

EGFR/EGFRvIII-targeted immunotoxin therapy for the treatment of glioblastomas via convection-enhanced delivery
por: Bao, Xuhui, et al.
Publicado: (2016)

Novel role of hematopoietic stem cells in immunologic rejection of malignant gliomas
por: Flores, Catherine, et al.
Publicado: (2015)

Effect of Helicobacter pylori infection on pregnancy rates and early pregnancy loss after intracytoplasmic sperm injection
por: Hajishafiha, Masomeh, et al.
Publicado: (2011)

Toxin-Based Targeted Therapy for Malignant Brain Tumors
por: Chandramohan, Vidyalakshmi, et al.
Publicado: (2012)

Silencing of AJAP1 expression by promoter methylation activates the Wnt/β-catenin signaling pathway to promote tumor proliferation and metastasis in salivary adenoid cystic carcinoma
por: Jiang, Liehao, et al.
Publicado: (2023)

THER-05. GENETICALLY STABLE POLIOVIRUS VECTOR CARRYING H3.3K27M ANTIGEN FOR TREATMENT OF DIFFUSE MIDLINE GLIOMA BY INTRAMUSCULAR INJECTION
por: Mosaheb, Mubeen, et al.
Publicado: (2020)

Role of iron supplementation in promoting maternal and fetal outcome
por: Yekta, Zahra, et al.
Publicado: (2011)

A novel bispecific antibody recruits T cells to eradicate tumors in the “immunologically privileged” central nervous system
por: Choi, Bryan D., et al.
Publicado: (2013)

Resveratrol Impairs Glioma Stem Cells Proliferation and Motility by Modulating the Wnt Signaling Pathway
por: Cilibrasi, Chiara, et al.
Publicado: (2017)

Clinical utility of 5-aminolevulinic acid HCl to better visualize and more completely remove gliomas
por: Halani, Sameer H, et al.
Publicado: (2016)

Application of mutagen sensitivity assay in a glioma case-control study
por: Erdal, Serap, et al.
Publicado: (2018)

MTSS1 is epigenetically regulated in glioma cells and inhibits glioma cell motility
por: Luxen, Daniel, et al.
Publicado: (2016)

Aberrant Otx2 Expression Enhances Migration and Induces Ectopic Proliferation of Hindbrain Neuronal Progenitor Cells
por: Wortham, Matthew, et al.
Publicado: (2012)

Mechanisms of invasion and motility of high-grade gliomas in the brain
por: Mair, Devin B., et al.
Publicado: (2018)

Pharmacologic modulation of motility.
por: McCallum, R. W.
Publicado: (1999)

Microflora Modulation of Motility
por: Quigley, Eamonn M M
Publicado: (2011)

Bone Marrow–generated Dendritic Cells Pulsed with Tumor Extracts or Tumor RNA Induce Antitumor Immunity against Central Nervous System Tumors
por: Ashley, David M., et al.
Publicado: (1997)

Monitoring Radiographic Brain Tumor Progression
por: Mehta, Ankit I., et al.
Publicado: (2011)

Decoupling of DNA damage response signaling from DNA damages underlies temozolomide resistance in glioblastoma cells()
por: Cui, Bo, et al.
Publicado: (2010)

Regulatory T cells are redirected to kill glioblastoma by an EGFRvIII-targeted bispecific antibody
por: Choi, Bryan D, et al.
Publicado: (2013)

Elevated expression of podoplanin and its clinicopathological, prognostic, and therapeutic values in squamous non-small cell lung cancer
por: Xie, Liyi, et al.
Publicado: (2018)

Enzyme Redesign Guided by Cancer-Derived IDH1 Mutations
por: Reitman, Zachary J., et al.
Publicado: (2012)

SYST-14 D2C7 CAR EFFECTIVELY AND SAFELY TREATS EGFRWT AND EGFRVIII-EXPRESSING TUMORS FOLLOWING INTRACRANIAL ADMINISTRATION
por: Wilkinson, Daniel, et al.
Publicado: (2023)

Induction of the Unfolded Protein Response Drives Enhanced Metabolism and Chemoresistance in Glioma Cells
por: Epple, Laura M., et al.
Publicado: (2013)

Midkine expression in high grade gliomas: Correlation of this novel marker with proliferation and survival in human gliomas
por: Cheng, Yen-Po, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_6aqp9sshiobneg37i28nh7oaoc