A Novel DNA Aptamer for Dual Targeting of Polymorphonuclear Myeloid-derived Suppressor Cells and Tumor Cells

Aptamers have the potential to be used as targeting ligands for cancer treatment as they form unique spatial structures. Methods: In this study, a DNA aptamer (T1) that accumulates in the tumor microenvironment was identified through in vivo selection and validation in breast cancer models. The use...

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Detalles Bibliográficos
Autores principales: Liu, Haoran, Mai, Junhua, Shen, Jianliang, Wolfram, Joy, Li, Zhaoqi, Zhang, Guodong, Xu, Rong, Li, Yan, Mu, Chaofeng, Zu, Youli, Li, Xin, Lokesh, Ganesh L., Thiviyanathan, Varatharasa, Volk, David E., Gorenstein, David G., Ferrari, Mauro, Hu, Zhongbo, Shen, Haifa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743458/
https://www.ncbi.nlm.nih.gov/pubmed/29290791
http://dx.doi.org/10.7150/thno.21342

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