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Tumor-penetrating Peptide Conjugated and Doxorubicin Loaded T(1)-T(2) Dual Mode MRI Contrast Agents Nanoparticles for Tumor Theranostics
The conventional chemotherapeutics could not be traced in vivo and provide timely feedback on the clinical effectiveness of drugs. Methods: In this study, a tumor-penetrating peptide RGERPPR (RGE) modified, Gd-DTPA conjugated, and doxorubicin (DOX) loaded Fe(3)O(4)@SiO(2)@mSiO(2) nanoparticle drug d...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743462/ https://www.ncbi.nlm.nih.gov/pubmed/29290795 http://dx.doi.org/10.7150/thno.21074 |