Desacetylvinblastine Monohydrazide Disrupts Tumor Vessels by Promoting VE-cadherin Internalization

Vinca alkaloids, the well-known tubulin-binding agents, are widely used for the clinical treatment of malignant tumors. However, little attention has been paid to their vascular disrupting effects, and the underlying mechanisms remain largely unknown. This study aims to investigate the vascular disr...

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Detalles Bibliográficos
Autores principales: Lei, Xueping, Chen, Minfeng, Huang, Maohua, Li, Xiaobo, Shi, Changzheng, Zhang, Dong, Luo, Liangping, Zhang, Youwei, Ma, Nan, Chen, Heru, Liang, Huafeng, Ye, Wencai, Zhang, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743555/
https://www.ncbi.nlm.nih.gov/pubmed/29290815
http://dx.doi.org/10.7150/thno.22222

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