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Activity and Immune Correlates of a Programmed Death-1 Blockade Antibody in the treatment of Refractory Solid Tumors

Background: Blockade of programmed death 1 (PD-1), an inhibitory T lymphocyte receptor, is associated with immune system enhancement and tumor remission in various tumors. We assessed the anti-tumor activity and immune correlates of cancer patients treated with an anti-PD-1 antibody. Patients and Me...

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Detalles Bibliográficos
Autores principales: Jiang, Chang, Cai, Xiuyu, Zhang, Hongxia, Xia, Xiaojun, Zhang, Bei, Xia, Liangping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743729/
https://www.ncbi.nlm.nih.gov/pubmed/29290787
http://dx.doi.org/10.7150/jca.21414