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Zika Virus Infects, Activates, and Crosses Brain Microvascular Endothelial Cells, without Barrier Disruption

Zika virus (ZIKV) has been associated to central nervous system (CNS) harm, and virus was detected in the brain and cerebrospinal fluids of microcephaly and meningoencephalitis cases. However, the mechanism by which the virus reaches the CNS is unclear. Here, we addressed the effects of ZIKV replica...

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Detalles Bibliográficos
Autores principales: Papa, Michelle P., Meuren, Lana M., Coelho, Sharton V. A., Lucas, Carolina G. de Oliveira, Mustafá, Yasmin M., Lemos Matassoli, Flavio, Silveira, Paola P., Frost, Paula S., Pezzuto, Paula, Ribeiro, Milene R., Tanuri, Amilcar, Nogueira, Mauricio L., Campanati, Loraine, Bozza, Marcelo T., Paula Neto, Heitor A., Pimentel-Coelho, Pedro M., Figueiredo, Claudia P., de Aguiar, Renato S., de Arruda, Luciana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743735/
https://www.ncbi.nlm.nih.gov/pubmed/29312238
http://dx.doi.org/10.3389/fmicb.2017.02557