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Nivolumab Enhances In Vitro Effector Functions of PD-1(+) T-Lymphocytes and Leishmania-Infected Human Myeloid Cells in a Host Cell-Dependent Manner

Functional impairment of T-cells and a concomitant augmented expression of programmed death-1 (PD-1) have been observed in visceral leishmaniasis patients, as well as in experimental models for visceral and cutaneous leishmaniasis. The PD-1/PD-1-ligand (PD-1/PD-L) interaction negatively regulates T-...

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Detalles Bibliográficos
Autores principales:	Filippis, Christodoulos, Arens, Katharina, Noubissi Nzeteu, Gaetan Aime, Reichmann, Gabriele, Waibler, Zoe, Crauwels, Peter, van Zandbergen, Ger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743744/ https://www.ncbi.nlm.nih.gov/pubmed/29312350 http://dx.doi.org/10.3389/fimmu.2017.01880

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