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Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders
Appendage regeneration is one of the most compelling phenomena in regenerative biology and is extensively studied in axolotls and newts. However, the regenerative capacity in other families of salamanders remains poorly described. Here we characterize the limb regeneration process in Bolitoglossa ra...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743783/ https://www.ncbi.nlm.nih.gov/pubmed/29299325 http://dx.doi.org/10.1002/reg2.93 |
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author | Arenas Gómez, Claudia Marcela Gómez Molina, Andrea Zapata, Juliana D. Delgado, Jean Paul |
author_facet | Arenas Gómez, Claudia Marcela Gómez Molina, Andrea Zapata, Juliana D. Delgado, Jean Paul |
author_sort | Arenas Gómez, Claudia Marcela |
collection | PubMed |
description | Appendage regeneration is one of the most compelling phenomena in regenerative biology and is extensively studied in axolotls and newts. However, the regenerative capacity in other families of salamanders remains poorly described. Here we characterize the limb regeneration process in Bolitoglossa ramosi, a direct‐developing terrestrial salamander of the plethodontid family. We (1) describe the major morphological features at different stages of limb regeneration, (2) show that appendage regeneration in a terrestrial salamander varies from other amphibians and (3) show that limb regeneration in this species is considerably slower than in axolotls and newts (95 days post‐amputation for complete regeneration) despite having a significantly smaller genome size than axolotls or newts. |
format | Online Article Text |
id | pubmed-5743783 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57437832018-01-03 Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders Arenas Gómez, Claudia Marcela Gómez Molina, Andrea Zapata, Juliana D. Delgado, Jean Paul Regeneration (Oxf) Research Articles Appendage regeneration is one of the most compelling phenomena in regenerative biology and is extensively studied in axolotls and newts. However, the regenerative capacity in other families of salamanders remains poorly described. Here we characterize the limb regeneration process in Bolitoglossa ramosi, a direct‐developing terrestrial salamander of the plethodontid family. We (1) describe the major morphological features at different stages of limb regeneration, (2) show that appendage regeneration in a terrestrial salamander varies from other amphibians and (3) show that limb regeneration in this species is considerably slower than in axolotls and newts (95 days post‐amputation for complete regeneration) despite having a significantly smaller genome size than axolotls or newts. John Wiley and Sons Inc. 2017-12-06 /pmc/articles/PMC5743783/ /pubmed/29299325 http://dx.doi.org/10.1002/reg2.93 Text en © 2017 The Authors. Regeneration published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Arenas Gómez, Claudia Marcela Gómez Molina, Andrea Zapata, Juliana D. Delgado, Jean Paul Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders |
title | Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders |
title_full | Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders |
title_fullStr | Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders |
title_full_unstemmed | Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders |
title_short | Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders |
title_sort | limb regeneration in a direct‐developing terrestrial salamander, bolitoglossa ramosi (caudata: plethodontidae): limb regeneration in plethodontid salamanders |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743783/ https://www.ncbi.nlm.nih.gov/pubmed/29299325 http://dx.doi.org/10.1002/reg2.93 |
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