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Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders

Appendage regeneration is one of the most compelling phenomena in regenerative biology and is extensively studied in axolotls and newts. However, the regenerative capacity in other families of salamanders remains poorly described. Here we characterize the limb regeneration process in Bolitoglossa ra...

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Autores principales: Arenas Gómez, Claudia Marcela, Gómez Molina, Andrea, Zapata, Juliana D., Delgado, Jean Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743783/
https://www.ncbi.nlm.nih.gov/pubmed/29299325
http://dx.doi.org/10.1002/reg2.93
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author Arenas Gómez, Claudia Marcela
Gómez Molina, Andrea
Zapata, Juliana D.
Delgado, Jean Paul
author_facet Arenas Gómez, Claudia Marcela
Gómez Molina, Andrea
Zapata, Juliana D.
Delgado, Jean Paul
author_sort Arenas Gómez, Claudia Marcela
collection PubMed
description Appendage regeneration is one of the most compelling phenomena in regenerative biology and is extensively studied in axolotls and newts. However, the regenerative capacity in other families of salamanders remains poorly described. Here we characterize the limb regeneration process in Bolitoglossa ramosi, a direct‐developing terrestrial salamander of the plethodontid family. We (1) describe the major morphological features at different stages of limb regeneration, (2) show that appendage regeneration in a terrestrial salamander varies from other amphibians and (3) show that limb regeneration in this species is considerably slower than in axolotls and newts (95 days post‐amputation for complete regeneration) despite having a significantly smaller genome size than axolotls or newts.
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spelling pubmed-57437832018-01-03 Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders Arenas Gómez, Claudia Marcela Gómez Molina, Andrea Zapata, Juliana D. Delgado, Jean Paul Regeneration (Oxf) Research Articles Appendage regeneration is one of the most compelling phenomena in regenerative biology and is extensively studied in axolotls and newts. However, the regenerative capacity in other families of salamanders remains poorly described. Here we characterize the limb regeneration process in Bolitoglossa ramosi, a direct‐developing terrestrial salamander of the plethodontid family. We (1) describe the major morphological features at different stages of limb regeneration, (2) show that appendage regeneration in a terrestrial salamander varies from other amphibians and (3) show that limb regeneration in this species is considerably slower than in axolotls and newts (95 days post‐amputation for complete regeneration) despite having a significantly smaller genome size than axolotls or newts. John Wiley and Sons Inc. 2017-12-06 /pmc/articles/PMC5743783/ /pubmed/29299325 http://dx.doi.org/10.1002/reg2.93 Text en © 2017 The Authors. Regeneration published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Arenas Gómez, Claudia Marcela
Gómez Molina, Andrea
Zapata, Juliana D.
Delgado, Jean Paul
Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders
title Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders
title_full Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders
title_fullStr Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders
title_full_unstemmed Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders
title_short Limb regeneration in a direct‐developing terrestrial salamander, Bolitoglossa ramosi (Caudata: Plethodontidae): Limb regeneration in plethodontid salamanders
title_sort limb regeneration in a direct‐developing terrestrial salamander, bolitoglossa ramosi (caudata: plethodontidae): limb regeneration in plethodontid salamanders
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743783/
https://www.ncbi.nlm.nih.gov/pubmed/29299325
http://dx.doi.org/10.1002/reg2.93
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