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Promoter mutagenesis for fine‐tuning expression of essential genes in Mycobacterium tuberculosis

A range of regulated gene expression systems has been developed for mycobacteria in the last few years to facilitate the study of essential genes, validate novel drug targets and evaluate their vulnerability. Among these, the TetR/Pip‐OFF repressible promoter system was successfully used in several...

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Detalles Bibliográficos
Autores principales: Boldrin, Francesca, Degiacomi, Giulia, Serafini, Agnese, Kolly, Gaëlle S., Ventura, Marcello, Sala, Claudia, Provvedi, Roberta, Palù, Giorgio, Cole, Stewart T., Manganelli, Riccardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743821/
https://www.ncbi.nlm.nih.gov/pubmed/29076636
http://dx.doi.org/10.1111/1751-7915.12875