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Promoter mutagenesis for fine‐tuning expression of essential genes in Mycobacterium tuberculosis
A range of regulated gene expression systems has been developed for mycobacteria in the last few years to facilitate the study of essential genes, validate novel drug targets and evaluate their vulnerability. Among these, the TetR/Pip‐OFF repressible promoter system was successfully used in several...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743821/ https://www.ncbi.nlm.nih.gov/pubmed/29076636 http://dx.doi.org/10.1111/1751-7915.12875 |