Direct Fibrinolytic Snake Venom Metalloproteinases Affecting Hemostasis: Structural, Biochemical Features and Therapeutic Potential

Snake venom metalloproteinases (SVMPs) are predominant in viperid venoms, which provoke hemorrhage and affect hemostasis and thrombosis. P-I class enzymes consist only of a single metalloproteinase domain. Despite sharing high sequence homology, only some of them induce hemorrhage. They have direct...

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Detalles Bibliográficos
Autores principales: Sanchez, Eladio F., Flores-Ortiz, Renzo J., Alvarenga, Valeria G., Eble, Johannes A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744112/
https://www.ncbi.nlm.nih.gov/pubmed/29206190
http://dx.doi.org/10.3390/toxins9120392

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744112/
https://www.ncbi.nlm.nih.gov/pubmed/29206190
http://dx.doi.org/10.3390/toxins9120392

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