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Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering

Repair and regeneration of disorders affecting cardiac and pulmonary tissues through tissue-engineering-based approaches is currently of particular interest. On this matter, different families of bioactive glasses (BGs) have recently been given much consideration with respect to treating refractory...

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Autores principales: Kargozar, Saeid, Hamzehlou, Sepideh, Baino, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744364/
https://www.ncbi.nlm.nih.gov/pubmed/29244726
http://dx.doi.org/10.3390/ma10121429
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author Kargozar, Saeid
Hamzehlou, Sepideh
Baino, Francesco
author_facet Kargozar, Saeid
Hamzehlou, Sepideh
Baino, Francesco
author_sort Kargozar, Saeid
collection PubMed
description Repair and regeneration of disorders affecting cardiac and pulmonary tissues through tissue-engineering-based approaches is currently of particular interest. On this matter, different families of bioactive glasses (BGs) have recently been given much consideration with respect to treating refractory diseases of these tissues, such as myocardial infarction. The inherent properties of BGs, including their ability to bond to hard and soft tissues, to stimulate angiogenesis, and to elicit antimicrobial effects, along with their excellent biocompatibility, support these newly proposed strategies. Moreover, BGs can also act as a bioactive reinforcing phase to finely tune the mechanical properties of polymer-based constructs used to repair the damaged cardiac and pulmonary tissues. In the present study, we evaluated the potential of different forms of BGs, alone or in combination with other materials (e.g., polymers), in regards to repair and regenerate injured tissues of cardiac and pulmonary systems.
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spelling pubmed-57443642017-12-31 Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering Kargozar, Saeid Hamzehlou, Sepideh Baino, Francesco Materials (Basel) Review Repair and regeneration of disorders affecting cardiac and pulmonary tissues through tissue-engineering-based approaches is currently of particular interest. On this matter, different families of bioactive glasses (BGs) have recently been given much consideration with respect to treating refractory diseases of these tissues, such as myocardial infarction. The inherent properties of BGs, including their ability to bond to hard and soft tissues, to stimulate angiogenesis, and to elicit antimicrobial effects, along with their excellent biocompatibility, support these newly proposed strategies. Moreover, BGs can also act as a bioactive reinforcing phase to finely tune the mechanical properties of polymer-based constructs used to repair the damaged cardiac and pulmonary tissues. In the present study, we evaluated the potential of different forms of BGs, alone or in combination with other materials (e.g., polymers), in regards to repair and regenerate injured tissues of cardiac and pulmonary systems. MDPI 2017-12-15 /pmc/articles/PMC5744364/ /pubmed/29244726 http://dx.doi.org/10.3390/ma10121429 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kargozar, Saeid
Hamzehlou, Sepideh
Baino, Francesco
Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering
title Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering
title_full Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering
title_fullStr Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering
title_full_unstemmed Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering
title_short Potential of Bioactive Glasses for Cardiac and Pulmonary Tissue Engineering
title_sort potential of bioactive glasses for cardiac and pulmonary tissue engineering
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744364/
https://www.ncbi.nlm.nih.gov/pubmed/29244726
http://dx.doi.org/10.3390/ma10121429
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