NNT is a key regulator of adrenal redox homeostasis and steroidogenesis in male mice

Nicotinamide nucleotide transhydrogenase, NNT, is a ubiquitous protein of the inner mitochondrial membrane with a key role in mitochondrial redox balance. NNT produces high concentrations of NADPH for detoxification of reactive oxygen species by glutathione and thioredoxin pathways. In humans, NNT d...

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Detalles Bibliográficos
Autores principales: Meimaridou, E, Goldsworthy, M, Chortis, V, Fragouli, E, Foster, P A, Arlt, W, Cox, R, Metherell, L A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744559/
https://www.ncbi.nlm.nih.gov/pubmed/29046340
http://dx.doi.org/10.1530/JOE-16-0638

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