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Overexpression of Map3k7 activates sinoatrial node-like differentiation in mouse ES-derived cardiomyocytes

In vivo, cardiomyocytes comprise a heterogeneous population of contractile cells defined by unique electrophysiologies, molecular markers and morphologies. The mechanisms directing myocardial cells to specific sub-lineages remain poorly understood. Here we report that overexpression of TGFβ-Activate...

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Detalles Bibliográficos
Autores principales: Brown, Kemar, Legros, Stephanie, Ortega, Francis A., Dai, Yunkai, Doss, Michael Xavier, Christini, David J., Robinson, Richard B., Foley, Ann C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744947/
https://www.ncbi.nlm.nih.gov/pubmed/29281682
http://dx.doi.org/10.1371/journal.pone.0189818

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