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Shuffling Active Site Substate Populations Affects Catalytic Activity: The Case of Glucose Oxidase
[Image: see text] Glucose oxidase has wide applications in the pharmaceutical, chemical, and food industries. Many recent studies have enhanced key properties of this enzyme using directed evolution, yet without being able to reveal why these mutations are actually beneficial. This work presents a s...
Autores principales: | Petrović, Dušan, Frank, David, Kamerlin, Shina Caroline Lynn, Hoffmann, Kurt, Strodel, Birgit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2017
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745072/ https://www.ncbi.nlm.nih.gov/pubmed/29291138 http://dx.doi.org/10.1021/acscatal.7b01575 |
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