Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm

The noncoding genome is pervasively transcribed. Noncoding RNAs (ncRNAs) generated from enhancers have been proposed as a general facet of enhancer function and some have been shown to be required for enhancer activity. Here we examine the transcription-factor-(TF)-dependence of ncRNA expression to...

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Detalles Bibliográficos
Autores principales: Yang, Xinan H, Nadadur, Rangarajan D, Hilvering, Catharina RE, Bianchi, Valerio, Werner, Michael, Mazurek, Stefan R, Gadek, Margaret, Shen, Kaitlyn M, Goldman, Joseph Aaron, Tyan, Leonid, Bekeny, Jenna, Hall, Johnathon M, Lee, Nutishia, Perez-Cervantes, Carlos, Burnicka-Turek, Ozanna, Poss, Kenneth D, Weber, Christopher R, de Laat, Wouter, Ruthenburg, Alexander J, Moskowitz, Ivan P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745077/
https://www.ncbi.nlm.nih.gov/pubmed/29280435
http://dx.doi.org/10.7554/eLife.31683

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