Shigella entry unveils a calcium/calpain-dependent mechanism for inhibiting sumoylation

Disruption of the sumoylation/desumoylation equilibrium is associated with several disease states such as cancer and infections, however the mechanisms regulating the global SUMO balance remain poorly defined. Here, we show that infection by Shigella flexneri, the causative agent of human bacillary...

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Detalles Bibliográficos
Autores principales: Lapaquette, Pierre, Fritah, Sabrina, Lhocine, Nouara, Andrieux, Alexandra, Nigro, Giulia, Mounier, Joëlle, Sansonetti, Philippe, Dejean, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745084/
https://www.ncbi.nlm.nih.gov/pubmed/29231810
http://dx.doi.org/10.7554/eLife.27444

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745084/
https://www.ncbi.nlm.nih.gov/pubmed/29231810
http://dx.doi.org/10.7554/eLife.27444

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