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SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a

Ras proteins play vital roles in numerous biological processes and Ras mutations are found in many human tumors. Understanding how Ras proteins are regulated is important for elucidating cell signaling pathways and identifying new targets for treating human diseases. Here we report that one of the K...

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Detalles Bibliográficos
Autores principales:	Jing, Hui, Zhang, Xiaoyu, Wisner, Stephanie A, Chen, Xiao, Spiegelman, Nicole A, Linder, Maurine E, Lin, Hening
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Biochemistry and Chemical Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745086/ https://www.ncbi.nlm.nih.gov/pubmed/29239724 http://dx.doi.org/10.7554/eLife.32436

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