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Inhibiting the Ca(2+) Influx Induced by Human CSF
One potential therapeutic strategy for Alzheimer’s disease (AD) is to use antibodies that bind to small soluble protein aggregates to reduce their toxic effects. However, these therapies are rarely tested in human CSF before clinical trials because of the lack of sensitive methods that enable the me...
Autores principales: | Drews, Anna, De, Suman, Flagmeier, Patrick, Wirthensohn, David C., Chen, Wei-Hsin, Whiten, Daniel R., Rodrigues, Margarida, Vincke, Cécile, Muyldermans, Serge, Paterson, Ross W., Slattery, Catherine F., Fox, Nick C., Schott, Jonathan M., Zetterberg, Henrik, Dobson, Christopher M., Gandhi, Sonia, Klenerman, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745229/ https://www.ncbi.nlm.nih.gov/pubmed/29241555 http://dx.doi.org/10.1016/j.celrep.2017.11.057 |
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