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Glucocorticoid Receptor Binding Induces Rapid and Prolonged Large-Scale Chromatin Decompaction at Multiple Target Loci

Glucocorticoids act by binding to the glucocorticoid receptor (GR), which binds to specific motifs within enhancers of target genes to activate transcription. Previous studies have suggested that GRs can promote interactions between gene promoters and distal elements within target loci. In contrast,...

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Detalles Bibliográficos
Autores principales:	Jubb, Alasdair W., Boyle, Shelagh, Hume, David A., Bickmore, Wendy A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745231/ https://www.ncbi.nlm.nih.gov/pubmed/29241532 http://dx.doi.org/10.1016/j.celrep.2017.11.053

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