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Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture

AIM: To determine morbidity and mortality in hip fracture patients and also to assess for any independent associations between Do-Not-Resuscitate (DNR) status and increased post-operative morbidity and mortality in patients undergoing surgical repair of hip fractures. METHODS: We conducted a propens...

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Autores principales: Brovman, Ethan Y, Pisansky, Andrew J, Beverly, Anair, Bader, Angela M, Urman, Richard D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745433/
https://www.ncbi.nlm.nih.gov/pubmed/29312849
http://dx.doi.org/10.5312/wjo.v8.i12.902
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author Brovman, Ethan Y
Pisansky, Andrew J
Beverly, Anair
Bader, Angela M
Urman, Richard D
author_facet Brovman, Ethan Y
Pisansky, Andrew J
Beverly, Anair
Bader, Angela M
Urman, Richard D
author_sort Brovman, Ethan Y
collection PubMed
description AIM: To determine morbidity and mortality in hip fracture patients and also to assess for any independent associations between Do-Not-Resuscitate (DNR) status and increased post-operative morbidity and mortality in patients undergoing surgical repair of hip fractures. METHODS: We conducted a propensity score matched retrospective analysis using de-identified data from the American College of Surgeons’ National Surgical Quality Improvement Project (ACS NSQIP) for all patients undergoing hip fracture surgery over a 7 year period in hospitals across the United States enrolled in the ACS NSQIP with and without DNR status. We measured patient demographics including DNR status, co-morbidities, frailty and functional baseline, surgical and anaesthetic procedure data, post-operative morbidity/complications, length of stay, discharge destination and mortality. RESULTS: Of 9218 patients meeting the inclusion criteria, 13.6% had a DNR status, 86.4% did not. Mortality was higher in the DNR compared to the non-DNR group, at 15.3% vs 8.1% and propensity score matched multivariable analysis demonstrated that DNR status was independently associated with mortality (OR = 2.04, 95%CI: 1.46-2.86, P < 0.001). Additionally, analysis of the propensity score matched cohort demonstrated that DNR status was associated with a significant, but very small increased likelihood of post-operative complications (0.53 vs 0.43 complications per episode; OR = 1.21; 95%CI: 1.04-1.41, P = 0.004). Cardiopulmonary resuscitation and unplanned reintubation were significantly less likely in patients with DNR status. CONCLUSION: While DNR status patients had higher rates of post-operative complications and mortality, DNR status itself was not otherwise associated with increased morbidity. DNR status appears to increase 30-d mortality via ceilings of care in keeping with a DNR status, including withholding reintubation and cardiopulmonary resuscitation.
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spelling pubmed-57454332018-01-08 Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture Brovman, Ethan Y Pisansky, Andrew J Beverly, Anair Bader, Angela M Urman, Richard D World J Orthop Retrospective Cohort Study AIM: To determine morbidity and mortality in hip fracture patients and also to assess for any independent associations between Do-Not-Resuscitate (DNR) status and increased post-operative morbidity and mortality in patients undergoing surgical repair of hip fractures. METHODS: We conducted a propensity score matched retrospective analysis using de-identified data from the American College of Surgeons’ National Surgical Quality Improvement Project (ACS NSQIP) for all patients undergoing hip fracture surgery over a 7 year period in hospitals across the United States enrolled in the ACS NSQIP with and without DNR status. We measured patient demographics including DNR status, co-morbidities, frailty and functional baseline, surgical and anaesthetic procedure data, post-operative morbidity/complications, length of stay, discharge destination and mortality. RESULTS: Of 9218 patients meeting the inclusion criteria, 13.6% had a DNR status, 86.4% did not. Mortality was higher in the DNR compared to the non-DNR group, at 15.3% vs 8.1% and propensity score matched multivariable analysis demonstrated that DNR status was independently associated with mortality (OR = 2.04, 95%CI: 1.46-2.86, P < 0.001). Additionally, analysis of the propensity score matched cohort demonstrated that DNR status was associated with a significant, but very small increased likelihood of post-operative complications (0.53 vs 0.43 complications per episode; OR = 1.21; 95%CI: 1.04-1.41, P = 0.004). Cardiopulmonary resuscitation and unplanned reintubation were significantly less likely in patients with DNR status. CONCLUSION: While DNR status patients had higher rates of post-operative complications and mortality, DNR status itself was not otherwise associated with increased morbidity. DNR status appears to increase 30-d mortality via ceilings of care in keeping with a DNR status, including withholding reintubation and cardiopulmonary resuscitation. Baishideng Publishing Group Inc 2017-12-18 /pmc/articles/PMC5745433/ /pubmed/29312849 http://dx.doi.org/10.5312/wjo.v8.i12.902 Text en ©The Author(s) 2017. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ Open-Access: This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
spellingShingle Retrospective Cohort Study
Brovman, Ethan Y
Pisansky, Andrew J
Beverly, Anair
Bader, Angela M
Urman, Richard D
Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture
title Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture
title_full Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture
title_fullStr Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture
title_full_unstemmed Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture
title_short Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture
title_sort do-not-resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture
topic Retrospective Cohort Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745433/
https://www.ncbi.nlm.nih.gov/pubmed/29312849
http://dx.doi.org/10.5312/wjo.v8.i12.902
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