Cargando…

The Extracellular Domain of Human High Affinity Copper Transporter (hNdCTR1), Synthesized by E. coli Cells, Chelates Silver and Copper Ions In Vivo

There is much interest in effective copper chelators to correct copper dyshomeostasis in neurodegenerative and oncological diseases. In this study, a recombinant fusion protein for expression in Escherichia coli cells was constructed from glutathione-S-transferase (GST) and the N-terminal domain (ec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sankova, Tatiana P., Orlov, Iurii A., Saveliev, Andrey N., Kirilenko, Demid A., Babich, Polina S., Brunkov, Pavel N., Puchkova, Ludmila V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745460/ https://www.ncbi.nlm.nih.gov/pubmed/29099786 http://dx.doi.org/10.3390/biom7040078

Ejemplares similares

New silver nanoparticles induce apoptosis-like process in E. coli and interfere with mammalian copper metabolism
por: Orlov, Iurii A, et al.
Publicado: (2016)

Size-Dependent Bioactivity of Silver Nanoparticles: Antibacterial Properties, Influence on Copper Status in Mice, and Whole-Body Turnover
por: Skomorokhova, Ekaterina A, et al.
Publicado: (2020)

CRISP-R/Cas9 Mediated Deletion of Copper Transport Genes CTR1 and DMT1 in NSCLC Cell Line H1299. Biological and Pharmacological Consequences
por: Ilyechova, Ekaterina Y., et al.
Publicado: (2019)

Copper Metabolism of Newborns Is Adapted to Milk Ceruloplasmin as a Nutritive Source of Copper: Overview of the Current Data
por: Puchkova, Ludmila V., et al.
Publicado: (2018)

Copper-Dependent Trafficking of the Ctr4-Ctr5 Copper Transporting Complex
por: Ioannoni, Raphaël, et al.
Publicado: (2010)

Abnormalities in Copper Status Associated with an Elevated Risk of Parkinson’s Phenotype Development
por: Karpenko, Marina N., et al.
Publicado: (2023)

X-ray structures of the high-affinity copper transporter Ctr1
por: Ren, Feifei, et al.
Publicado: (2019)

Tryptophan Scanning Analysis of the Membrane Domain of CTR-Copper Transporters
por: De Feo, Christopher J., et al.
Publicado: (2010)

The Rhizophagus irregularis Genome Encodes Two CTR Copper Transporters That Mediate Cu Import Into the Cytosol and a CTR-Like Protein Likely Involved in Copper Tolerance
por: Gómez-Gallego, Tamara, et al.
Publicado: (2019)

Regulation of the high-affinity copper transporter (hCtr1) expression by cisplatin and heavy metals
por: Liang, Zheng Dong, et al.
Publicado: (2013)

Phylogenetic Analysis of Six-Domain Multi-Copper Blue Proteins
por: Vasin, Andrey, et al.
Publicado: (2013)

The Features of Copper Metabolism in the Rat Liver during Development
por: Zatulovskaia, Yulia A., et al.
Publicado: (2015)

CTR1 Silencing Inhibits Angiogenesis by Limiting Copper Entry into Endothelial Cells
por: Narayanan, Gomathy, et al.
Publicado: (2013)

Copper/MYC/CTR1 interplay: a dangerous relationship in hepatocellular carcinoma
por: Porcu, Cristiana, et al.
Publicado: (2018)

The C-Terminus of Human Copper Importer Ctr1 Acts as a Binding Site and Transfers Copper to Atox1
por: Kahra, Dana, et al.
Publicado: (2016)

Copper chelation in patients with hypertrophic cardiomyopathy
por: Reid, Anna, et al.
Publicado: (2022)

Dynamical interplay between the human high-affinity copper transporter hCtr1 and its cognate metal ion
por: Walke, Gulshan, et al.
Publicado: (2022)

The Crossroads between Host Copper Metabolism and Influenza Infection
por: Puchkova, Ludmila V., et al.
Publicado: (2021)

Copper–zinc superoxide dismutase (Sod1) activation terminates interaction between its copper chaperone (Ccs) and the cytosolic metal-binding domain of the copper importer Ctr1
por: Skopp, Amélie, et al.
Publicado: (2019)

Molecular and functional analyses of COPT/Ctr-type copper transporter-like gene family in rice
por: Yuan, Meng, et al.
Publicado: (2011)

The copper transporter CTR1 and cisplatin accumulation at the single-cell level by LA-ICP-TOFMS
por: Schoeberl, Anna, et al.
Publicado: (2022)

Copper transporter Ctr1 contributes to enhancement of the sensitivity of cisplatin in esophageal squamous cell carcinoma
por: Wang, Xin, et al.
Publicado: (2023)

Current Biomedical Use of Copper Chelation Therapy
por: Baldari, Silvia, et al.
Publicado: (2020)

Transcriptional Responses of Copper-Transport-Related Genes ctr1, ctr2 and atox1 and Their Roles in the Regulation of Cu Homeostasis in Yellow Catfish Pelteobagrus fulvidraco
por: Yang, Hong, et al.
Publicado: (2022)

Silver Ions as a Tool for Understanding Different Aspects of Copper Metabolism
por: Puchkova, Ludmila V., et al.
Publicado: (2019)

The role of subcutaneous adipose tissue in supporting the copper balance in rats with a chronic deficiency in holo-ceruloplasmin
por: Ilyechova, Ekaterina Y., et al.
Publicado: (2017)

The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart
por: Baker, Zakery N, et al.
Publicado: (2017)

Chelation of Theranostic Copper Radioisotopes with S-Rich Macrocycles: From Radiolabelling of Copper-64 to In Vivo Investigation
por: Tosato, Marianna, et al.
Publicado: (2022)

Chelators for copper radionuclides in positron emission tomography radiopharmaceuticals()
por: Cai, Zhengxin, et al.
Publicado: (2013)

Iron and Copper Intracellular Chelation as an Anticancer Drug Strategy
por: Gaur, Kavita, et al.
Publicado: (2018)

Graphene Amination towards Its Grafting by Antibodies for Biosensing Applications
por: Rabchinskii, Maxim K., et al.
Publicado: (2023)

EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer
por: Wang, Xuemin, et al.
Publicado: (2015)

Integrin αV modulates the cellular pharmacology of copper and cisplatin by regulating expression of the influx transporter CTR1
por: Lin, Xinjian, et al.
Publicado: (2014)

The copper transport-associated protein Ctr4 can form prion-like epigenetic determinants in Schizosaccharomyces pombe
por: Sideri, Theodora, et al.
Publicado: (2017)

Host Cell Copper Transporters CTR1 and ATP7A are important for Influenza A virus replication
por: Rupp, Jonathan C., et al.
Publicado: (2017)

Chronic Corticosterone Exposure Suppresses Copper Transport through GR-Mediated Intestinal CTR1 Pathway in Mice
por: Guo, Shihui, et al.
Publicado: (2023)

Diabetic cardiomyopathy is associated with defective myocellular copper regulation and both defects are rectified by divalent copper chelation
por: Zhang, Shaoping, et al.
Publicado: (2014)

Exploring Mannosylpurines as Copper Chelators and Cholinesterase Inhibitors with Potential for Alzheimer’s Disease
por: Schino, Ignazio, et al.
Publicado: (2022)

The Case for Abandoning Therapeutic Chelation of Copper Ions in Alzheimer's Disease
por: Drew, Simon C.
Publicado: (2017)

Hypopituitarism in Wilson’s disease resolved after copper-chelating therapy
por: Dauth, Nina, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jctssbjr2s1ncnn7td154h6q8p