Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection

Strong adherence to a Mediterranean diet is associated with improved cognitive function and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources of polyphenols which are responsible in part for the beneficial effects on cognitive functioning. Polyphenols induce en...

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Autores principales: Martínez-Huélamo, Miriam, Rodríguez-Morató, Jose, Boronat, Anna, de la Torre, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745483/
https://www.ncbi.nlm.nih.gov/pubmed/28954417
http://dx.doi.org/10.3390/antiox6040073
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author Martínez-Huélamo, Miriam
Rodríguez-Morató, Jose
Boronat, Anna
de la Torre, Rafael
author_facet Martínez-Huélamo, Miriam
Rodríguez-Morató, Jose
Boronat, Anna
de la Torre, Rafael
author_sort Martínez-Huélamo, Miriam
collection PubMed
description Strong adherence to a Mediterranean diet is associated with improved cognitive function and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources of polyphenols which are responsible in part for the beneficial effects on cognitive functioning. Polyphenols induce endogenous antioxidant defense mechanisms by modulating transcription factors such as the nuclear factor (erythroid-derived 2)-like 2 (Nrf2). This review discusses the scientific data supporting the modulating effect of olive oil and red wine polyphenols on Nrf2 expression, and the potential health benefits associated with cognitive functioning.
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spelling pubmed-57454832018-01-02 Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection Martínez-Huélamo, Miriam Rodríguez-Morató, Jose Boronat, Anna de la Torre, Rafael Antioxidants (Basel) Review Strong adherence to a Mediterranean diet is associated with improved cognitive function and a lower prevalence of mild cognitive impairment. Olive oil and red wine are rich sources of polyphenols which are responsible in part for the beneficial effects on cognitive functioning. Polyphenols induce endogenous antioxidant defense mechanisms by modulating transcription factors such as the nuclear factor (erythroid-derived 2)-like 2 (Nrf2). This review discusses the scientific data supporting the modulating effect of olive oil and red wine polyphenols on Nrf2 expression, and the potential health benefits associated with cognitive functioning. MDPI 2017-09-26 /pmc/articles/PMC5745483/ /pubmed/28954417 http://dx.doi.org/10.3390/antiox6040073 Text en © 2017 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Martínez-Huélamo, Miriam
Rodríguez-Morató, Jose
Boronat, Anna
de la Torre, Rafael
Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection
title Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection
title_full Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection
title_fullStr Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection
title_full_unstemmed Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection
title_short Modulation of Nrf2 by Olive Oil and Wine Polyphenols and Neuroprotection
title_sort modulation of nrf2 by olive oil and wine polyphenols and neuroprotection
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745483/
https://www.ncbi.nlm.nih.gov/pubmed/28954417
http://dx.doi.org/10.3390/antiox6040073
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