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Knowledge, attitudes and practices of community pharmacists on generic medicines in Palestine: a cross-sectional study
BACKGROUND: Generic substitution in several countries has become a common practice. Besides, it is considered as a major cost minimizing strategy meant to contain pharmaceutical expenditure without compromising healthcare quality. However, the safety and quality issues of generic products are of top...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745619/ https://www.ncbi.nlm.nih.gov/pubmed/29282055 http://dx.doi.org/10.1186/s12913-017-2813-z |
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author | Shraim, Naser Y. Al Taha, Tasneem A. Qawasmeh, Rawan F. Jarrar, Hiba N. Shtaya, Maram A. N. Shayeb, Lama A. Sweileh, Waleed M. |
author_facet | Shraim, Naser Y. Al Taha, Tasneem A. Qawasmeh, Rawan F. Jarrar, Hiba N. Shtaya, Maram A. N. Shayeb, Lama A. Sweileh, Waleed M. |
author_sort | Shraim, Naser Y. |
collection | PubMed |
description | BACKGROUND: Generic substitution in several countries has become a common practice. Besides, it is considered as a major cost minimizing strategy meant to contain pharmaceutical expenditure without compromising healthcare quality. However, the safety and quality issues of generic products are of top concerns of general practitioners and health work professionals. This study aimed to investigate community pharmacist’s knowledge, attitudes and practices toward generic medicines in Palestine. METHODS: This study was a cross-sectional observational study employing a self-administered questionnaire. The questionnaire was of four main sections: demographic and practice details of the participants, knowledge, attitudes and the influencing factors related to selection and dispensing of generic medicines. A convenience sampling technique was implemented in this study in which the data collection form was distributed in West Bank- Palestine among a set of practicing pharmacists. Mann-Whitney-U or Kruskal-Wallis tests were used to comparison of different issues as appropriate. P-values of <0.05 were considered significant. RESULTS: A total of 302 community pharmacists were interviewed, slightly more than half were males (52.3%). The mean knowledge score of participants regarding generic medicines was (5.91 ± 1.27) where the highest score was 8 of 10. Knowledge score was not significantly influenced by any of the socio-demographic characteristics. Our data showed that most of included pharmacists in the study (95.4%) agreed that health authorities should implement bioequivalence policies prior to marketing approval of generics, while 87.4% of participants agreed that they should be given the right to substitute generics and the majority (62.3%) support generic substitution for brand name drugs in all cases when a generic is available The main two factors affect pharmacists’ selection and dispensing of generic medicines are personal faith in the product (86.1%) and cost effectiveness of generic medicines (84.1%). CONCLUSIONS: Generic medicines substitution among pharmacists is widespread and prevalent. Our data found that participant pharmacists in Palestine had basic knowledge with regards to generic medicine. However, their knowledge score pertaining the technical and regulatory aspects of bioequivalence and pharmacokinetic parameters in particular was insufficient. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12913-017-2813-z) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5745619 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-57456192018-01-03 Knowledge, attitudes and practices of community pharmacists on generic medicines in Palestine: a cross-sectional study Shraim, Naser Y. Al Taha, Tasneem A. Qawasmeh, Rawan F. Jarrar, Hiba N. Shtaya, Maram A. N. Shayeb, Lama A. Sweileh, Waleed M. BMC Health Serv Res Research Article BACKGROUND: Generic substitution in several countries has become a common practice. Besides, it is considered as a major cost minimizing strategy meant to contain pharmaceutical expenditure without compromising healthcare quality. However, the safety and quality issues of generic products are of top concerns of general practitioners and health work professionals. This study aimed to investigate community pharmacist’s knowledge, attitudes and practices toward generic medicines in Palestine. METHODS: This study was a cross-sectional observational study employing a self-administered questionnaire. The questionnaire was of four main sections: demographic and practice details of the participants, knowledge, attitudes and the influencing factors related to selection and dispensing of generic medicines. A convenience sampling technique was implemented in this study in which the data collection form was distributed in West Bank- Palestine among a set of practicing pharmacists. Mann-Whitney-U or Kruskal-Wallis tests were used to comparison of different issues as appropriate. P-values of <0.05 were considered significant. RESULTS: A total of 302 community pharmacists were interviewed, slightly more than half were males (52.3%). The mean knowledge score of participants regarding generic medicines was (5.91 ± 1.27) where the highest score was 8 of 10. Knowledge score was not significantly influenced by any of the socio-demographic characteristics. Our data showed that most of included pharmacists in the study (95.4%) agreed that health authorities should implement bioequivalence policies prior to marketing approval of generics, while 87.4% of participants agreed that they should be given the right to substitute generics and the majority (62.3%) support generic substitution for brand name drugs in all cases when a generic is available The main two factors affect pharmacists’ selection and dispensing of generic medicines are personal faith in the product (86.1%) and cost effectiveness of generic medicines (84.1%). CONCLUSIONS: Generic medicines substitution among pharmacists is widespread and prevalent. Our data found that participant pharmacists in Palestine had basic knowledge with regards to generic medicine. However, their knowledge score pertaining the technical and regulatory aspects of bioequivalence and pharmacokinetic parameters in particular was insufficient. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12913-017-2813-z) contains supplementary material, which is available to authorized users. BioMed Central 2017-12-28 /pmc/articles/PMC5745619/ /pubmed/29282055 http://dx.doi.org/10.1186/s12913-017-2813-z Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Shraim, Naser Y. Al Taha, Tasneem A. Qawasmeh, Rawan F. Jarrar, Hiba N. Shtaya, Maram A. N. Shayeb, Lama A. Sweileh, Waleed M. Knowledge, attitudes and practices of community pharmacists on generic medicines in Palestine: a cross-sectional study |
title | Knowledge, attitudes and practices of community pharmacists on generic medicines in Palestine: a cross-sectional study |
title_full | Knowledge, attitudes and practices of community pharmacists on generic medicines in Palestine: a cross-sectional study |
title_fullStr | Knowledge, attitudes and practices of community pharmacists on generic medicines in Palestine: a cross-sectional study |
title_full_unstemmed | Knowledge, attitudes and practices of community pharmacists on generic medicines in Palestine: a cross-sectional study |
title_short | Knowledge, attitudes and practices of community pharmacists on generic medicines in Palestine: a cross-sectional study |
title_sort | knowledge, attitudes and practices of community pharmacists on generic medicines in palestine: a cross-sectional study |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745619/ https://www.ncbi.nlm.nih.gov/pubmed/29282055 http://dx.doi.org/10.1186/s12913-017-2813-z |
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