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Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures
BACKGROUND: During multiple sclerosis (MS) lesion formation, inflammatory mediators are produced by microglial cells and invading leukocytes. Subsequently, hypertrophic astrocytes fill the lesion and produce extracellular matrix (ECM) proteins that together form the astroglial scar. This is benefici...
Autores principales: | Espitia Pinzón, Nathaly, Brevé, John J. P., Bol, John G. J. M., Drukarch, Benjamin, Baron, Wia, van Dam, Anne-Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745633/ https://www.ncbi.nlm.nih.gov/pubmed/29282083 http://dx.doi.org/10.1186/s12974-017-1031-2 |
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