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The Rap activator Gef26 regulates synaptic growth and neuronal survival via inhibition of BMP signaling

In Drosophila, precise regulation of BMP signaling is essential for normal synaptic growth at the larval neuromuscular junction (NMJ) and neuronal survival in the adult brain. However, the molecular mechanisms underlying fine-tuning of BMP signaling in neurons remain poorly understood. We show that...

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Detalles Bibliográficos
Autores principales: Heo, Keunjung, Nahm, Minyeop, Lee, Min-Jung, Kim, Young-Eun, Ki, Chang-Seok, Kim, Seung Hyun, Lee, Seungbok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745669/
https://www.ncbi.nlm.nih.gov/pubmed/29282074
http://dx.doi.org/10.1186/s13041-017-0342-7