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Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature
OBJECTIVE: To evaluate the IUI success factors relative to controlled ovarian stimulation (COS) and infertility type, this retrospective cohort study included 1251 couples undergoing homologous IUI. RESULTS: We achieved 13% clinical pregnancies and 11% live births. COS and infertility type do not ha...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745683/ https://www.ncbi.nlm.nih.gov/pubmed/29387719 http://dx.doi.org/10.1155/2017/3512784 |
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author | Cabry-Goubet, Rosalie Scheffler, Florence Belhadri-Mansouri, Naima Belloc, Stephanie Lourdel, Emmanuelle Devaux, Aviva Chahine, Hickmat De Mouzon, Jacques Copin, Henri Benkhalifa, Moncef |
author_facet | Cabry-Goubet, Rosalie Scheffler, Florence Belhadri-Mansouri, Naima Belloc, Stephanie Lourdel, Emmanuelle Devaux, Aviva Chahine, Hickmat De Mouzon, Jacques Copin, Henri Benkhalifa, Moncef |
author_sort | Cabry-Goubet, Rosalie |
collection | PubMed |
description | OBJECTIVE: To evaluate the IUI success factors relative to controlled ovarian stimulation (COS) and infertility type, this retrospective cohort study included 1251 couples undergoing homologous IUI. RESULTS: We achieved 13% clinical pregnancies and 11% live births. COS and infertility type do not have significant effect on IUI clinical outcomes with unstable intervention of various couples' parameters, including the female age, the IUI attempt rank, and the sperm quality. CONCLUSION: Further, the COS used seemed a weak predictor for IUI success; therefore, the indications need more discussion, especially in unexplained infertility cases involving various factors. Indeed, the fourth IUI attempt, the female age over 40 years, and the total motile sperm count <5 × 10(6) were critical in decreasing the positive clinical outcomes of IUI. Those parameter cut-offs necessitate a larger analysis to give infertile couples more chances through IUI before carrying out other ART techniques. |
format | Online Article Text |
id | pubmed-5745683 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-57456832018-01-31 Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature Cabry-Goubet, Rosalie Scheffler, Florence Belhadri-Mansouri, Naima Belloc, Stephanie Lourdel, Emmanuelle Devaux, Aviva Chahine, Hickmat De Mouzon, Jacques Copin, Henri Benkhalifa, Moncef Biomed Res Int Research Article OBJECTIVE: To evaluate the IUI success factors relative to controlled ovarian stimulation (COS) and infertility type, this retrospective cohort study included 1251 couples undergoing homologous IUI. RESULTS: We achieved 13% clinical pregnancies and 11% live births. COS and infertility type do not have significant effect on IUI clinical outcomes with unstable intervention of various couples' parameters, including the female age, the IUI attempt rank, and the sperm quality. CONCLUSION: Further, the COS used seemed a weak predictor for IUI success; therefore, the indications need more discussion, especially in unexplained infertility cases involving various factors. Indeed, the fourth IUI attempt, the female age over 40 years, and the total motile sperm count <5 × 10(6) were critical in decreasing the positive clinical outcomes of IUI. Those parameter cut-offs necessitate a larger analysis to give infertile couples more chances through IUI before carrying out other ART techniques. Hindawi 2017 2017-12-13 /pmc/articles/PMC5745683/ /pubmed/29387719 http://dx.doi.org/10.1155/2017/3512784 Text en Copyright © 2017 Rosalie Cabry-Goubet et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Cabry-Goubet, Rosalie Scheffler, Florence Belhadri-Mansouri, Naima Belloc, Stephanie Lourdel, Emmanuelle Devaux, Aviva Chahine, Hickmat De Mouzon, Jacques Copin, Henri Benkhalifa, Moncef Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature |
title | Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature |
title_full | Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature |
title_fullStr | Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature |
title_full_unstemmed | Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature |
title_short | Effect of Gonadotropin Types and Indications on Homologous Intrauterine Insemination Success: A Study from 1251 Cycles and a Review of the Literature |
title_sort | effect of gonadotropin types and indications on homologous intrauterine insemination success: a study from 1251 cycles and a review of the literature |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745683/ https://www.ncbi.nlm.nih.gov/pubmed/29387719 http://dx.doi.org/10.1155/2017/3512784 |
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