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Matrine combined with cisplatin synergistically inhibited urothelial bladder cancer cells via down-regulating VEGF/PI3K/Akt signaling pathway
BACKGROUND: Cisplatin is one of the first-line drugs for urothelial bladder cancer (UBC) treatment. However, its considerable side effects and the emergence of drug resistance are becoming major limitations for its application. This study aimed to investigate whether matrine and cisplatin could pres...
Autores principales: | Liao, Xiao-Zhong, Tao, Lan-Ting, Liu, Jia-Hui, Gu, Yue-Yu, Xie, Jun, Chen, Yuling, Lin, Mei-Gui, Liu, Tao-Li, Wang, Dong-Mei, Guo, Hai-Yan, Mo, Sui-Lin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745706/ https://www.ncbi.nlm.nih.gov/pubmed/29299027 http://dx.doi.org/10.1186/s12935-017-0495-6 |
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