Docosahexaenoic acid reduces sterol regulatory element binding protein-1 and fatty acid synthase expression and inhibits cell proliferation by inhibiting pAkt signaling in a human breast cancer MCF-7 cell line

BACKGROUND: Fatty acid synthase (FASN), the major enzyme in de novo fatty acid synthesis, is highly expressed in breast cancer and its expression is reduced by polyunsaturated fatty acids (PUFAs) in liver. We previously found a positive association between rat mammary tumor levels of the n-6 PUFA ar...

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Detalles Bibliográficos
Autores principales: Huang, Li-Hsuan, Chung, Hsin-Yun, Su, Hui-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745739/
https://www.ncbi.nlm.nih.gov/pubmed/29282029
http://dx.doi.org/10.1186/s12885-017-3936-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745739/
https://www.ncbi.nlm.nih.gov/pubmed/29282029
http://dx.doi.org/10.1186/s12885-017-3936-7

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