Is dopamine transporter-mediated dopaminergic signaling in the retina a noninvasive biomarker for attention-deficit/ hyperactivity disorder? A study in a novel dopamine transporter variant Val559 transgenic mouse model

BACKGROUND: Dopamine (DA) is a critical neuromodulator in the retina. Disruption of retinal DA synthesis and signaling significantly attenuates light-adapted, electroretinogram (ERG) responses, as well as contrast sensitivity and acuity. As these measures can be detected noninvasively, they may prov...

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Detalles Bibliográficos
Autores principales: Dai, Heng, Jackson, Chad R., Davis, Gwynne L., Blakely, Randy D., McMahon, Douglas G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745861/
https://www.ncbi.nlm.nih.gov/pubmed/29281965
http://dx.doi.org/10.1186/s11689-017-9215-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745861/
https://www.ncbi.nlm.nih.gov/pubmed/29281965
http://dx.doi.org/10.1186/s11689-017-9215-8

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