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Is dopamine transporter-mediated dopaminergic signaling in the retina a noninvasive biomarker for attention-deficit/ hyperactivity disorder? A study in a novel dopamine transporter variant Val559 transgenic mouse model

BACKGROUND: Dopamine (DA) is a critical neuromodulator in the retina. Disruption of retinal DA synthesis and signaling significantly attenuates light-adapted, electroretinogram (ERG) responses, as well as contrast sensitivity and acuity. As these measures can be detected noninvasively, they may prov...

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Detalles Bibliográficos
Autores principales:	Dai, Heng, Jackson, Chad R., Davis, Gwynne L., Blakely, Randy D., McMahon, Douglas G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745861/ https://www.ncbi.nlm.nih.gov/pubmed/29281965 http://dx.doi.org/10.1186/s11689-017-9215-8

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