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Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection

We describe a 36-year-old woman with a relapsing Hodgkin’s lymphoma who developed a severe bilateral sudden visual loss almost three weeks after the initiation of brentuximab therapy. Ancillary fundus tests yielded bilateral severe retinal arteriolar occlusion 360° and serous macular retinal detachm...

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Detalles Bibliográficos
Autores principales: Ayhan, Ziya, Kaya, Sureyya Yigit, Ozcan, Mehmet Ali, Saatci, Ali Osman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745970/
https://www.ncbi.nlm.nih.gov/pubmed/29326861
http://dx.doi.org/10.3205/oc000080
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author Ayhan, Ziya
Kaya, Sureyya Yigit
Ozcan, Mehmet Ali
Saatci, Ali Osman
author_facet Ayhan, Ziya
Kaya, Sureyya Yigit
Ozcan, Mehmet Ali
Saatci, Ali Osman
author_sort Ayhan, Ziya
collection PubMed
description We describe a 36-year-old woman with a relapsing Hodgkin’s lymphoma who developed a severe bilateral sudden visual loss almost three weeks after the initiation of brentuximab therapy. Ancillary fundus tests yielded bilateral severe retinal arteriolar occlusion 360° and serous macular retinal detachment. No visual improvement could be achieved despite the pulse corticosteroid therapy and a single bilateral intravitreal aflibercept administration cessation of the brentuximab therapy. Unfortunately, she succumbed to respiratory failure almost six weeks after the diagnosis of Purtscher-like retinopathy.
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spelling pubmed-57459702018-01-11 Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection Ayhan, Ziya Kaya, Sureyya Yigit Ozcan, Mehmet Ali Saatci, Ali Osman GMS Ophthalmol Cases Article We describe a 36-year-old woman with a relapsing Hodgkin’s lymphoma who developed a severe bilateral sudden visual loss almost three weeks after the initiation of brentuximab therapy. Ancillary fundus tests yielded bilateral severe retinal arteriolar occlusion 360° and serous macular retinal detachment. No visual improvement could be achieved despite the pulse corticosteroid therapy and a single bilateral intravitreal aflibercept administration cessation of the brentuximab therapy. Unfortunately, she succumbed to respiratory failure almost six weeks after the diagnosis of Purtscher-like retinopathy. German Medical Science GMS Publishing House 2017-12-15 /pmc/articles/PMC5745970/ /pubmed/29326861 http://dx.doi.org/10.3205/oc000080 Text en Copyright © 2017 Ayhan et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License. See license information at http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Ayhan, Ziya
Kaya, Sureyya Yigit
Ozcan, Mehmet Ali
Saatci, Ali Osman
Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection
title Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection
title_full Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection
title_fullStr Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection
title_full_unstemmed Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection
title_short Brentuximab vedotin related bilateral Purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection
title_sort brentuximab vedotin related bilateral purtscher-like retinopathy unresponsive to pulse steroid therapy and intravitreal aflibercept injection
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5745970/
https://www.ncbi.nlm.nih.gov/pubmed/29326861
http://dx.doi.org/10.3205/oc000080
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