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Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders that share genetic risk factors and pathological hallmarks. Intriguingly, these shared factors result in a high rate of comorbidity of these diseases in patients. Intracellular protein aggregates ar...

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Detalles Bibliográficos
Autores principales: Deng, Zhiqiang, Sheehan, Patricia, Chen, Shi, Yue, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746010/
https://www.ncbi.nlm.nih.gov/pubmed/29282133
http://dx.doi.org/10.1186/s13024-017-0232-6