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Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?
Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are neurodegenerative disorders that share genetic risk factors and pathological hallmarks. Intriguingly, these shared factors result in a high rate of comorbidity of these diseases in patients. Intracellular protein aggregates ar...
Autores principales: | Deng, Zhiqiang, Sheehan, Patricia, Chen, Shi, Yue, Zhenyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746010/ https://www.ncbi.nlm.nih.gov/pubmed/29282133 http://dx.doi.org/10.1186/s13024-017-0232-6 |
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