Cargando…
P38 delta MAPK promotes breast cancer progression and lung metastasis by enhancing cell proliferation and cell detachment
The protein p38 mitogen-activated protein kinase delta isoform (p38δ) is a poorly studied member of the MAPK family. Data analysis from The Cancer Genome Atlas (TCGA) database revealed that p38δ is highly expressed in all types of human breast cancers. Using a human breast cancer tissue array, we co...
Autores principales: | Wada, Masayuki, Canals, Daniel, Adada, Mohamad, Coant, Nicolas, Salama, Mohamed F, Helke, Kristi L, Arthur, J. Simon C., Shroyer, Kenneth R, Kitatani, Kazuyuki, Obeid, Lina M, Hannun, Yusuf A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746050/ https://www.ncbi.nlm.nih.gov/pubmed/28783172 http://dx.doi.org/10.1038/onc.2017.274 |
Ejemplares similares
-
Activation of p38 Mitogen-Activated Protein Kinase in Gaucher’s Disease
por: Kitatani, Kazuyuki, et al.
Publicado: (2015) -
AKT as a key target for growth promoting functions of neutral ceramidase in colon cancer cells
por: Coant, Nicolas, et al.
Publicado: (2018) -
Defining a role for sphingosine kinase 1 in p53-dependent tumors
por: Heffernan-Stroud, Linda A., et al.
Publicado: (2011) -
MKK3 sustains cell proliferation and survival through p38DELTA MAPK activation in colorectal cancer
por: Stramucci, Lorenzo, et al.
Publicado: (2019) -
Distinct Roles for Hematopoietic and Extra-Hematopoietic Sphingosine Kinase-1 in Inflammatory Bowel Disease
por: Snider, Ashley J., et al.
Publicado: (2014)