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MicroRNA-410-3p attenuates gemcitabine resistance in pancreatic ductal adenocarcinoma by inhibiting HMGB1-mediated autophagy

Gemcitabine-based chemotherapy is the most common treatment option for pancreatic ductal adenocarcinoma (PDAC). However, it offers little therapeutic value in many cases due to the rapid development of chemoresistance. MicroRNAs (miRNAs) have been found to play pivotal roles in the chemotherapeutic...

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Detalles Bibliográficos
Autores principales: Xiong, Junjie, Wang, Dan, Wei, Ailin, Ke, Nengwen, Wang, Yichao, Tang, Jie, He, Sirong, Hu, Weiming, Liu, Xubao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746084/
https://www.ncbi.nlm.nih.gov/pubmed/29296182
http://dx.doi.org/10.18632/oncotarget.22494