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MicroRNA-410-3p attenuates gemcitabine resistance in pancreatic ductal adenocarcinoma by inhibiting HMGB1-mediated autophagy
Gemcitabine-based chemotherapy is the most common treatment option for pancreatic ductal adenocarcinoma (PDAC). However, it offers little therapeutic value in many cases due to the rapid development of chemoresistance. MicroRNAs (miRNAs) have been found to play pivotal roles in the chemotherapeutic...
Autores principales: | Xiong, Junjie, Wang, Dan, Wei, Ailin, Ke, Nengwen, Wang, Yichao, Tang, Jie, He, Sirong, Hu, Weiming, Liu, Xubao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746084/ https://www.ncbi.nlm.nih.gov/pubmed/29296182 http://dx.doi.org/10.18632/oncotarget.22494 |
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