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Effect modification by region in the associations of LEP G2548A and LEPR Q223R polymorphisms with statin-induced CK elevation

We investigated the associations of LEP G2548A and LEPR Q223R polymorphisms with statin-induced creatine kinase (CK) elevation among Chinese patients with hyperlipidemia. A total of587 enrolled individuals were treated with 20 mg/d oral simvastatin for 8 consecutive weeks. Genotyping of LEP G2548A a...

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Detalles Bibliográficos
Autores principales: Jiang, Shanqun, Venners, Scott A., Li, Kang, Hsu, Yi-Hsiang, Weinstock, Justin, Zou, Yanfeng, Pan, Faming, Xu, Xiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746089/
https://www.ncbi.nlm.nih.gov/pubmed/29296187
http://dx.doi.org/10.18632/oncotarget.22506

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