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Changes in PD-L1 expression according to tumor infiltrating lymphocytes of acquired EGFR-TKI resistant EGFR-mutant non-small-cell lung cancer

BACKGROUNDS: EGFR-mutant non-small cell lung cancer (NSCLC) that developed acquired resistance to EGFR-tyrosine kinase (TKI) are potential candidates for programmed death 1 (PD1) inhibitor. RESULTS: TPS≥1% for PD-L1 and low CD8(+) TIL in post-TKI tumor showed a trend for a lower PFS of EGFR-TKIs (14...

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Detalles Bibliográficos
Autores principales:	Kim, Tae-Jung, Hong, Soon Auck, Kim, Okran, Kim, Seung Joon, Yang, Ji-Hyun, Joung, Eun Kyo, Kang, Jin-Hyoung, Hong, Sook-Hee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746096/ https://www.ncbi.nlm.nih.gov/pubmed/29296194 http://dx.doi.org/10.18632/oncotarget.22582

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