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The pathogenesis of diclofenac induced immunoallergic hepatitis in a canine model of liver injury

Hypersensitivity to non-steroidal anti-inflammatory drugs is a common adverse drug reaction and may result in serious inflammatory reactions of the liver. To investigate mechanism of immunoallergic hepatitis beagle dogs were given 1 or 3 mg/kg/day (HD) oral diclofenac for 28 days. HD diclofenac trea...

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Detalles Bibliográficos
Autores principales: Selvaraj, Saravanakumar, Oh, Jung-Hwa, Spanel, Reinhard, Länger, Florian, Han, Hyoung-Yun, Lee, Eun-Hee, Yoon, Seokjoo, Borlak, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746105/
https://www.ncbi.nlm.nih.gov/pubmed/29296203
http://dx.doi.org/10.18632/oncotarget.21201

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