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Dormant glioblastoma cells acquire stem cell characteristics and are differentially affected by Temozolomide and AT101 treatment

Cellular dormancy is defined as a state in which cells enter quiescence driven by intrinsic or extrinsic factors, and striking parallels exist between the concept of cellular dormancy in malignancies and the cancer stem cell theory. We showed now that the proven dormancy markers insulin-like growth...

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Detalles Bibliográficos
Autores principales: Adamski, Vivian, Hempelmann, Annika, Flüh, Charlotte, Lucius, Ralph, Synowitz, Michael, Hattermann, Kirsten, Held-Feindt, Janka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746126/
https://www.ncbi.nlm.nih.gov/pubmed/29296224
http://dx.doi.org/10.18632/oncotarget.22514