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Effects of three IL-15 variants on NCI-H446 cell proliferation and expression of cell cycle regulatory molecules
Interleukin 15 (IL-15) is a cytokine exhibiting antitumor characteristic similar to that of IL-2. However, in human tissues and cells, IL-15 expression and secretion is very limited, suggesting IL-15 functions mainly intracellularly. In the present study, we assessed the effects of transfecting NCI-...
Autores principales: | Ding, Jun-Ying, Wang, Zhi-Hua, Zhang, Zheng-Zheng, Cui, Xu-Ran, Hong, Yan-Ying, Liu, Qing-Quan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746129/ https://www.ncbi.nlm.nih.gov/pubmed/29296227 http://dx.doi.org/10.18632/oncotarget.22550 |
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