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CYP51 is an essential drug target for the treatment of primary amoebic meningoencephalitis (PAM)

Primary Amoebic Meningoencephalitis (PAM) is caused by Naegleria fowleri, a free-living amoeba that occasionally infects humans. While considered “rare” (but likely underreported) the high mortality rate and lack of established success in treatment makes PAM a particularly devastating infection. In...

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Detalles Bibliográficos
Autores principales: Debnath, Anjan, Calvet, Claudia M., Jennings, Gareth, Zhou, Wenxu, Aksenov, Alexander, Luth, Madeline R., Abagyan, Ruben, Nes, W. David, McKerrow, James H., Podust, Larissa M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746216/
https://www.ncbi.nlm.nih.gov/pubmed/29284029
http://dx.doi.org/10.1371/journal.pntd.0006104