DNase-capture reveals differential transcription factor binding modalities

We describe DNase-capture, an assay that increases the analytical resolution of DNase-seq by focusing its sequencing phase on selected genomic regions. We introduce a new method to compensate for capture bias called BaseNormal that allows for accurate recovery of transcription factor protection prof...

Descripción completa

Detalles Bibliográficos
Autores principales: Kang, Daniel, Sherwood, Richard, Barkal, Amira, Hashimoto, Tatsunori, Engstrom, Logan, Gifford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746236/
https://www.ncbi.nlm.nih.gov/pubmed/29284001
http://dx.doi.org/10.1371/journal.pone.0187046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746236/
https://www.ncbi.nlm.nih.gov/pubmed/29284001
http://dx.doi.org/10.1371/journal.pone.0187046

Ejemplares similares