SM22α suppresses cytokine-induced inflammation and the transcription of NF-κB inducing kinase (Nik) by modulating SRF transcriptional activity in vascular smooth muscle cells

Vascular smooth muscle cell (VSMC) phenotypic modulation is characterized by the downregulation of SMC actin cytoskeleton proteins. Our published study shows that depletion of SM22α (aka SM22, Transgelin, an actin cytoskeleton binding protein) promotes inflammation in SMCs by activating NF-κB signal...

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Detalles Bibliográficos
Autores principales: Dai, Xiaohua, Thiagarajan, Devi, Fang, Jingye, Shen, Jianbin, Annam, Neeraja Priyanka, Yang, Zhao, Jiang, Hong, Ju, Donghong, Xie, Youming, Zhang, Kezhong, Tseng, Yan Yuan, Yang, Zhe, Rishi, Arun K., Li, Hui J., Yang, Maozhou, Li, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5746259/
https://www.ncbi.nlm.nih.gov/pubmed/29284006
http://dx.doi.org/10.1371/journal.pone.0190191

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